org.apache.http.NoHttpResponseException: server-address:80 failed to respond - JMeter

I am running a load test using Jmeter 5.2 on a web application. When I run the thread group even with a greater than 500 thread, I do some configuration jmeter : in user.properties I have set : httpclient4.retrycount=1

hc.parameters.file=hc.parameters

In hc.parameters I have set:

http.connection.stalecheck$Boolean=true

and in Http request : client Implementation > httpClient4

 org.apache.http.NoHttpResponseException: recette-autohiring.novelis.io:80 failed to respond
        at org.apache.http.impl.conn.DefaultHttpResponseParser.parseHead(DefaultHttpResponseParser.java:141)
        at org.apache.http.impl.conn.DefaultHttpResponseParser.parseHead(DefaultHttpResponseParser.java:56)
        at org.apache.http.impl.io.AbstractMessageParser.parse(AbstractMessageParser.java:259)
        at org.apache.http.impl.DefaultBHttpClientConnection.receiveResponseHeader(DefaultBHttpClientConnection.java:163)
        at org.apache.http.impl.conn.CPoolProxy.receiveResponseHeader(CPoolProxy.java:157)
        at org.apache.http.protocol.HttpRequestExecutor.doReceiveResponse(HttpRequestExecutor.java:273)
        at org.apache.http.protocol.HttpRequestExecutor.execute(HttpRequestExecutor.java:125)
        at org.apache.http.impl.execchain.MainClientExec.execute(MainClientExec.java:272)
        at org.apache.http.impl.execchain.ProtocolExec.execute(ProtocolExec.java:186)
        at org.apache.http.impl.execchain.RetryExec.execute(RetryExec.java:89)
        at org.apache.http.impl.execchain.RedirectExec.execute(RedirectExec.java:110)
        at org.apache.http.impl.client.InternalHttpClient.doExecute(InternalHttpClient.java:185)
        at org.apache.http.impl.client.CloseableHttpClient.execute(CloseableHttpClient.java:83)
        at org.apache.jmeter.protocol.http.sampler.HTTPHC4Impl.executeRequest(HTTPHC4Impl.java:850)
        at org.apache.jmeter.protocol.http.sampler.HTTPHC4Impl.sample(HTTPHC4Impl.java:561)
        at org.apache.jmeter.protocol.http.sampler.HTTPSamplerProxy.sample(HTTPSamplerProxy.java:67)
        at org.apache.jmeter.protocol.http.sampler.HTTPSamplerBase.sample(HTTPSamplerBase.java:1282)
        at org.apache.jmeter.protocol.http.sampler.HTTPSamplerBase.sample(HTTPSamplerBase.java:1271)
        at org.apache.jmeter.threads.JMeterThread.doSampling(JMeterThread.java:627)
        at org.apache.jmeter.threads.JMeterThread.executeSamplePackage(JMeterThread.java:551)
        at org.apache.jmeter.threads.JMeterThread.processSampler(JMeterThread.java:490)
        at org.apache.jmeter.threads.JMeterThread.run(JMeterThread.java:257)
        at java.lang.Thread.run(Unknown Source)

any idea how to resolve this!