Java automated testing of C++ GUI

Is it possible to run automation testing on a GUI that doesn't use pixels as references on where to click?

I want to be able to move the GUI window anywhere on the desktop that isn't in the exact pixel location and run the automation. I'm not sure how I would be able to get Java to 'see' the GUI how it is and acknowledge which buttons to click.

I haven't found anything that can actually run automation that isn't based on pixels.